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Generic form of buspirone ). The antidepressant effects of buspirone are buy buspirone 10mg mediated, at least in part, order buspirone through activity at the serotonin 2C receptor. In this study, the authors found that treatment conferred dose-dependent reductions in global Hamilton Depression Rating Scale (HAM-D) scores with a range of mean effect size values −4.1 (−5.0 to −3.7) in the fluoxetine subgroup and 3.3 (−6.5 to −2.1) in the placebo treatment group. Furthermore, reduction of depressive symptoms was significantly greater in patients treated with buspirone than in the placebo group, with mean overall effect size value of −5.1 (−6.3 to −3.7) in patients treated with buspirone compared −2.4 (−4.4 to −1.5) in the placebo group. The authors conclude that their findings suggest buspirone may be of clinical value as a potential treatment for major depressive disorder, and that their data support the hypothesis that mechanism of action may involve its pharmacological activity generic of buspar at the serotonin 2C receptor.

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